During the peripartum period, metabolic stress develops as a result of negative energy balance, followed by excessive fat mobilization and reduced productive performance. Excessive lipolysis leads to immune suppression, abnormal regulation of inflammation, and increased oxidative stress.
The animal’s natural antioxidant system is not able to adequately cope with this condition.
The effects of rumen-limiting amino acids and choline on the regulation of immunity, antioxidant and anti-inflammatory status, and milk production performance have been widely studied in ruminants.
The transition phase of the dairy cow is an extremely delicate period, requiring a careful balance of supplied nutrients that must also take into account the condition of the gastrointestinal tract. The most recent research indicates that protection of the digestive system is a key factor for animal health and, consequently, for productive recovery.