{"id":25721,"date":"2026-10-22T10:31:07","date_gmt":"2026-10-22T08:31:07","guid":{"rendered":"https:\/\/www.tecnozoo.it\/2026\/10\/22\/oxidative-stress-in-dairy-cows-causes-damage-and-advanced-nutritional-strategies\/"},"modified":"2026-10-28T09:03:24","modified_gmt":"2026-10-28T08:03:24","slug":"oxidative-stress-in-dairy-cows-causes-damage-and-advanced-nutritional-strategies","status":"publish","type":"post","link":"https:\/\/www.tecnozoo.it\/en\/2026\/10\/22\/oxidative-stress-in-dairy-cows-causes-damage-and-advanced-nutritional-strategies\/","title":{"rendered":"Oxidative stress in dairy cows: causes, damage and advanced nutritional strategies"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"25721\" class=\"elementor elementor-25721 elementor-25710\" data-elementor-post-type=\"post\">\n\t\t\t\t<div class=\"elementor-element elementor-element-7733c20b e-flex e-con-boxed e-con e-parent\" data-id=\"7733c20b\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4b2f985f elementor-widget elementor-widget-text-editor\" data-id=\"4b2f985f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>The <strong>transition period<\/strong> \u2013 that is, the three weeks preceding and the three weeks following calving \u2013 represents the most delicate and crucial phase of the dairy cow\u2019s entire production cycle. Within this complex metabolic context, <strong>oxidative stress<\/strong> often acts as a silent trigger for a whole host of problems, including reduced milk yield and decreased fertility. <\/p><p>Nowadays, modern cattle farms can no longer afford to underestimate this phenomenon.<\/p><p>The targeted management of oxidative stress through the use of <strong>natural antioxidants and advanced phytochemicals<\/strong> helps to promote animal welfare and contributes to production efficiency and farm profitability.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3e0eafb elementor-widget elementor-widget-heading\" data-id=\"3e0eafb\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">What is oxidative stress and why does it affect dairy cows during the transition period?<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4dcc7ee elementor-widget elementor-widget-text-editor\" data-id=\"4dcc7ee\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Oxidative stress occurs when there is a significant imbalance within the body between the production of free radicals and the ability of the endogenous and exogenous antioxidant defence systems to neutralise them.<\/p><p>In dairy cows, this imbalance finds its ideal conditions during the <strong>transition period<\/strong>, and it is precisely at this stage that two critical events occur simultaneously:<br><br><\/p><ol><li><strong>The surge in energy and metabolic requirements<\/strong>: the onset of colostrum synthesis and lactation requires a massive expenditure of energy.<\/li><li><strong>Feed intake depression<\/strong>: for physiological and management-related reasons, dairy cows drastically reduce their dry matter intake in the days immediately around calving.<\/li><\/ol><p>This energy imbalance forces the animal to draw heavily on its bodily reserves (particularly adipose tissue) and, by triggering this metabolic process, the cow exponentially increases the production of free radicals at a cellular level.<\/p><p>This excess of ROS selectively attacks cellular structures, triggering <strong>lipid peroxidation of cell membranes<\/strong>, impairing tissue function and setting off a dangerous systemic inflammatory cascade.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a141539 elementor-widget elementor-widget-heading\" data-id=\"a141539\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Critical developments during calving<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e6c0a9c elementor-widget elementor-widget-text-editor\" data-id=\"e6c0a9c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Analysis of oxidative stress trends in dairy cows shows that levels of peroxides and free radicals begin to rise in the immediate pre-partum period, before surging dramatically and reaching their <strong>peak around five days after calving<\/strong>. It is precisely during this time frame that the cow\u2019s body is most vulnerable to metabolic disorders, infections and irreversible declines in reproductive performance. <\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-681add8 elementor-widget elementor-widget-heading\" data-id=\"681add8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">The economic and health implications on the farm<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f0567b6 elementor-widget elementor-widget-text-editor\" data-id=\"f0567b6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>A prolonged state of oxidative stress that is not properly managed has a significant impact on the farm\u2019s profit margins, affecting three main areas:<\/p><ul><li><strong>A drastic decline in fertility<\/strong>: free radicals damage oocytes and the uterine environment, seriously compromising key reproductive parameters such as the Conception Rate (CR) and the <em>Pregnancy Rate (PR)<\/em>. This results in a longer \u2018open period\u2019 and increased insemination costs. <\/li><li>Weakened immune system: an organism under oxidative stress responds inefficiently to pathogenic challenges, increasing the incidence of mastitis, retained placenta and metritis in the postpartum period.<\/li><li><strong>Loss of productive efficiency<\/strong>: reduced cell integrity and inflammatory processes divert precious energy and nutrients that would otherwise be channelled into milk production.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-48fd355 elementor-widget elementor-widget-heading\" data-id=\"48fd355\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">The key role of phytochemicals: polyphenols, salicylates and red grapevine in combating excess free radicals<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-22b737a elementor-widget elementor-widget-text-editor\" data-id=\"22b737a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>To effectively combat the damage caused by free radicals, modern animal nutrition moves beyond an approach based solely on synthetic substances and relies on the power of natural phytochemicals. Several scientific studies confirm the effectiveness of specific plant molecules in modulating metabolism and protecting cells: <\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e9946ce elementor-widget elementor-widget-heading\" data-id=\"e9946ce\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">1. Phenols and polyphenols from hydrolysed lignocellulose<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3a54f78 elementor-widget elementor-widget-text-editor\" data-id=\"3a54f78\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Lignin is a complex plant polymer consisting of phenylpropane units (coniferyl, coumaryl and sinapyl alcohols), the combination of which forms <strong>lignans<\/strong>. In nature, plants use these substances as a defensive barrier against fungi, bacteria and viruses, and as an antioxidant shield against solar radiation. When introduced into the <strong>diet of ruminants<\/strong>, lignans are beneficially modified by the ruminal and intestinal microflora, are subsequently absorbed, and exert a direct protective and antioxidant effect on cell membranes.  <\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-92dce90 elementor-widget elementor-widget-heading\" data-id=\"92dce90\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">2. Natural salicylates (White Willow and Meadowsweet)<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-236d833 elementor-widget elementor-widget-text-editor\" data-id=\"236d833\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Salicylic acid \u2013 a natural precursor of the well-known acetylsalicylic acid molecule \u2013 is traditionally extracted from the bark of the white willow (<em>Salix alba<\/em>) and from <em>Spirea ulmaria<\/em> (<em>Filipendula ulmaria<\/em>), which synthesise the substance to protect themselves from biotic and abiotic attacks. In dairy cows, natural salicylates act as powerful natural modulators of post-partum inflammation and fever, helping the animal to get through the critical phase without overburdening the liver. <\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b6d6eed elementor-widget elementor-widget-heading\" data-id=\"b6d6eed\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">3. Red Grape (Vitis vinifera)<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f9c4703 elementor-widget elementor-widget-text-editor\" data-id=\"f9c4703\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>An extraordinary plant-based concentrate that supports microcirculation and provides powerful natural antioxidants (anthocyanins and polyphenols), which work in perfect synergy with white willow and spirea.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0dabfda elementor-widget elementor-widget-heading\" data-id=\"0dabfda\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">A field trial with Normoterm Orac<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b23c316 elementor-widget elementor-widget-text-editor\" data-id=\"b23c316\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>To experience first-hand the benefits of a targeted nutritional strategy to combat oxidative stress, Tecnozoo \u2013 as part of a university thesis in collaboration with the Hungarian university Kaposv\u00e1ri Egyetem \u2013 monitored a field trial involving a group of Holstein dairy cows.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-75a3c94 elementor-widget elementor-widget-heading\" data-id=\"75a3c94\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">The application protocol<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a4036a2 elementor-widget elementor-widget-text-editor\" data-id=\"a4036a2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>The trial involved <span style=\"color: #e00000;\"><strong><a style=\"color: #e00000;\" href=\"https:\/\/www.tecnozoo.it\/en\/product\/normoterm-orac\/\">Normoterm Orac,<\/a><\/strong><\/span> which was administered according to a specific regimen:<\/p><ul><li><strong>al parto<\/strong>: 300 grammi per capo somministrati entro le prime 12 ore dal parto all&#8217;interno del <em>drench<\/em>.<\/li><li><strong>During the first 30 days of lactation<\/strong>: 50 grams per animal per day, mixed directly into the total mixed ration (TMR).<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-daa7f3e elementor-widget elementor-widget-heading\" data-id=\"daa7f3e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Maintaining wellbeing and business continuity<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6d48365 elementor-widget elementor-widget-text-editor\" data-id=\"6d48365\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Monitoring of physical and blood parameters during the trial showed that supplementation with antioxidant phytochemicals helps to:<\/p><ul><li>Supporting Total Antioxidant Status (TAS): by promoting the body\u2019s own ability to neutralise free radicals in the bloodstream.<\/li><li><strong>Supporting the normalisation of reproductive health<\/strong>: by promoting a natural return to normal rates of conception and pregnancy maintenance, thereby ensuring business continuity.<\/li><li>Protecting your investment in the dairy farm: supporting the cow\u2019s welfare during the transition period helps to minimise the costs arising from metabolic imbalances and to maximise the farm\u2019s efficiency<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f5c2723 elementor-widget elementor-widget-text-editor\" data-id=\"f5c2723\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p style=\"text-align: center;\"><strong>Protect your herd from the very first days after calving.<\/strong><\/p><p>Managing oxidative stress requires targeted nutritional strategies backed by sound scientific evidence. <strong>Contact Tecnozoo\u2019s team of nutritionists and vets<\/strong> to analyse the needs of your herd and devise the most suitable anti-stress protocol for your dairy cows.<\/p><p> <\/p><p> <\/p><p><em>Supporting studies and bibliography available on request.<\/em><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4c1c285 elementor-widget elementor-widget-chateau_core_button\" data-id=\"4c1c285\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"chateau_core_button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<a class=\"qodef-shortcode qodef-m  qodef-button qodef-layout--filled  qodef-html--link\" href=\"https:\/\/www.tecnozoo.it\/en\/contact-us\/\" target=\"_self\" data-hover-color=\"#FFFFFF\" style=\"color: #FFFFFF;background-color: #E7131A;border-color: #E2001A00\">\n\t<span class=\"qodef-m-text\">Contact us<\/span>\n<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-c5ac939 e-flex e-con-boxed e-con e-parent\" data-id=\"c5ac939\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>The transition period \u2013 that is, the three weeks preceding and the three weeks following calving \u2013 represents the most delicate and crucial phase of the dairy cow\u2019s entire production cycle. Within this complex metabolic context, oxidative stress often acts as a silent trigger for a whole host of problems, including reduced milk yield and [&hellip;]<\/p>\n","protected":false},"author":7,"featured_media":25723,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1083],"tags":[],"class_list":["post-25721","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-dairy-cows"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Oxidative stress in dairy cows: causes, damage and solutions<\/title>\n<meta name=\"description\" content=\"Find out how oxidative stress during the transition period affects dairy cows. 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